Loyola University researchers have identified the key components of a protein called TRIM5a that destroys HIV in rhesus monkeys.
The finding could lead to new TRIM5a-based treatments that would knock out HIV in humans, said senior researcher Edward M. Campbell, PhD, of Loyola University Health System.
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Humans also have TRIM5a, but while the human version of TRIM5a protects against some viruses, it does not protect against HIV.
There's always hope:
Researchers hope to turn TRIM5a into an effective therapeutic agent. But first they need to identify the components in TRIM5a that enable the protein to destroy viruses.
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